Niraparib tosylate

Catalog No.: A16618
PARP1/PARP2 inhibitor
Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Niraparib tosylate 5mg
$63.00
In stock
Niraparib tosylate 10mg
$109.00
In stock
Niraparib tosylate 50mg
$322.00
In stock
Niraparib tosylate 100mg
$644.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Niraparib tosylate has been cited by 1 publications
  • Laurie B Schenkel, .et al. , Cell Chem Biol, 2021, Mar 2;S2451-9456(21)00095-7 PMID: 33705687
  • Biological Activity
    Discription Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A16618
    Formula C26H28N4O4S
    Molecular Weight 492.59
    CAS Number 1038915-73-9
    SMILES NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O
    Synonyms MK-4827 tosylate
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 86 mg/mL (174.58 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.3 mL 101.5 mL 203.01 mL
    0.5 mM 4.06 mL 20.3 mL 40.6 mL
    1 mM 2.03 mL 10.15 mL 20.3 mL
    5 mM 0.41 mL 2.03 mL 4.06 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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