Alectinib Hydrochloride
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. |
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Catalog Num | A18000 |
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Formula | C30H35ClN4O2 |
Molecular Weight | 519.08 |
CAS Number | 1256589-74-8 |
SMILES | [H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1 |
Synonyms | CH5424802 Hydrochloride, CH 5424802, CH-5424802; RO5424802 Hydrochloride, RO 5424802, RO-5424802; AF-802 Hydrochloride, |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 2 mg/mL (3.85 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.26 mL | 96.32 mL | 192.65 mL |
0.5 mM | 3.85 mL | 19.26 mL | 38.53 mL |
1 mM | 1.93 mL | 9.63 mL | 19.26 mL |
5 mM | 0.39 mL | 1.93 mL | 3.85 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2