Ambroxol HCl

Catalog No.: A16398
Sodium Channel inhibitor
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 uM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
Grouped product items
Product Name Price Stock Qty
Ambroxol HCl 50mg
$30.00
In stock
Ambroxol HCl 100mg
$50.00
In stock
Ambroxol HCl 500mg
$200.00
In stock
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Adooq Products cited in reputable paper
Adooq's Ambroxol HCl has been cited by 1 publications
  • Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14
  • Biological Activity
    Discription AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 uM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
    Product Information
    Catalog Num A16398
    Formula C13H18Br2N2O.HCl
    Molecular Weight 414.56
    CAS Number 23828-92-4
    SMILES C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 4 mg/mL (9.64 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.12 mL 120.61 mL 241.22 mL
    0.5 mM 4.82 mL 24.12 mL 48.24 mL
    1 mM 2.41 mL 12.06 mL 24.12 mL
    5 mM 0.48 mL 2.41 mL 4.82 mL
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