Signaling Pathway
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| Discription | BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. | ||
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| Catalog Num | A18726 |
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| Formula | C20H19D3N8O3 |
| Molecular Weight | 425.46 |
| CAS Number | 1609392-27-9 |
| SMILES | O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H] |
| Synonyms | BMS-986165; BMS 986165; BMS986165; |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 27 mg/mL (63.46 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.5 mL | 117.52 mL | 235.04 mL |
| 0.5 mM | 4.7 mL | 23.5 mL | 47.01 mL |
| 1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
