CCT245737

Catalog No.: A17239
CHK1 inhibitor
CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor. CCT245737 showed CHK1 IC50 = 1.3 nM, CHK2 IC50 = 2440 nM, G2 check point abrogation IC50 = 30 nM. Mouse F (oral)=100%.
Grouped product items
Product Name Price Stock Qty
CCT245737 5mg
$90.00
In stock
CCT245737 10mg
$140.00
In stock
CCT245737 50mg
$450.00
In stock
CCT245737 100mg
$700.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor. CCT245737 showed CHK1 IC50 = 1.3 nM, CHK2 IC50 = 2440 nM, G2 check point abrogation IC50 = 30 nM. Mouse F (oral)=100%.
Targets
Target Value
Product Information
Catalog Num A17239
Formula C16H16F3N7O
Molecular Weight 379.3472
CAS Number 1489389-18-5
SMILES N#CC1=NC=C(NC2=NC=C(C(F)(F)F)C(NC[C@H]3CNCCO3)=C2)N=C1
Synonyms CCT 245737; CCT-245737
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 72 mg/mL (189.8 mM)
Water Insoluble
Ethanol Warmed: 9 mg/mL (23.72 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.36 mL 131.81 mL 263.61 mL
0.5 mM 5.27 mL 26.36 mL 52.72 mL
1 mM 2.64 mL 13.18 mL 26.36 mL
5 mM 0.53 mL 2.64 mL 5.27 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy CCT245737 | CCT245737 Supplier | purchase CCT245737 | CCT245737 cost | CCT245737 manufacturer | order CCT245737 | CCT245737 distributor | buy 1489389-18-5 | 1489389-18-5 Supplier | purchase 1489389-18-5 | 1489389-18-5 cost | 1489389-18-5 manufacturer | order 1489389-18-5 | 1489389-18-5 distributor