CHF5074

Catalog No.: A16214
γ-Secretase modulator
CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
Grouped product items
Product Name Price Stock Qty
CHF5074 5mg
$100.00
In stock
CHF5074 10mg
$150.00
In stock
CHF5074 50mg
$500.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
Product Information
Catalog Num A16214
Formula C16H11Cl2FO2
Molecular Weight 325.16
CAS Number 749269-83-8
SMILES O=C(C1(C2=CC=C(C3=CC=C(Cl)C(Cl)=C3)C(F)=C2)CC1)O
Synonyms CSP-1103, CHF-5074
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 51 mg/mL (156.84 mM)
Water Insoluble
Ethanol 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.75 mL 153.77 mL 307.54 mL
0.5 mM 6.15 mL 30.75 mL 61.51 mL
1 mM 3.08 mL 15.38 mL 30.75 mL
5 mM 0.62 mL 3.08 mL 6.15 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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