CHIR-99021 monohydrochloride
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | CHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. | ||
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Catalog Num | A21430 |
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Formula | C22H19Cl3N8 |
Molecular Weight | 501.8 |
CAS Number | 1797989-42-4 |
SMILES | N#CC1=CC=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)N=C1.[H]Cl |
Synonyms | CHIR99021, CHIR 99021, CT99021 monohydrochloride, CT 99021, CT-99021 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 89 mg/mL (177.36 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (3.98 mM) | ||
In vivo | 5% DMSO+30% PEG 300+ddH2O | 22 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.93 mL | 99.64 mL | 199.28 mL |
0.5 mM | 3.99 mL | 19.93 mL | 39.86 mL |
1 mM | 1.99 mL | 9.96 mL | 19.93 mL |
5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2