Cobimetinib hemifumarate

Name: Cobimetinib hemifumarate
SKU: A18033
Price: 108 USD
Rating: 5 (288 reviews)

Catalog No.: A18033

MEK1 inhibitor

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

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Grouped product items
Product Name	Price	Stock
Cobimetinib hemifumarate 5mg	$108.00	In stock
Cobimetinib hemifumarate 10mg	$186.00	In stock
Cobimetinib hemifumarate 50mg	$552.00	In stock
Cobimetinib hemifumarate 100mg	$1,104.00	In stock
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Data Sheet

SDS

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Biological Activity

Discription

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

Targets

Target	Value

Product Information

Catalog Num	A18033
Formula	C25H25F3IN3O6
Molecular Weight	647.38
CAS Number	1369665-02-0
SMILES	OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O.O=C(O)/C=C/C(O)=O.[0.5]
Synonyms	GDC-0973 hemifumarate, GDC0973, GDC 0973; XL-518 hemifumarate, XL518, XL 518
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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