Dithranol
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Anthralin, also known as Dithranol, is a hepsin activity inhibitor used for treatment of psoriasis Inhibition of hepsin activity suppresses the invasive growth of the tumor. Anthralin exerts a direct effect on keratinocytes and leukocytes. Anthralin significantly prolonged the prophase of mitotic keratinocytes in subtoxic doses and suppressed the expression of keratin 6 mRNA in the immediately suprabasal layer of psoriatic epidermis in vivo. Anthralin also inhibits the transformation of lymphocytes and the release of reactive oxygen species from activated leukocytes, in vitro. |
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Catalog Num | A17404 |
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Formula | C14H10O3 |
Molecular Weight | 226.231 |
CAS Number | 1143-38-0 |
SMILES | O=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13 |
Synonyms | Anthralin; Batridol; Dithranol; NSC 629313; NSC-629313; NSC629313 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 6 mg/mL (26.52 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 44.2 mL | 221.01 mL | 442.03 mL |
0.5 mM | 8.84 mL | 44.2 mL | 88.41 mL |
1 mM | 4.42 mL | 22.1 mL | 44.2 mL |
5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2