EGFR-IN-7
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity. | ||
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Targets |
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Catalog Num | A18562 |
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Formula | C32H41BrN9O2P |
Molecular Weight | 694.6 |
CAS Number | 2267329-76-8 |
SMILES | CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Insoluble | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 14.4 mL | 71.98 mL | 143.97 mL |
0.5 mM | 2.88 mL | 14.4 mL | 28.79 mL |
1 mM | 1.44 mL | 7.2 mL | 14.4 mL |
5 mM | 0.29 mL | 1.44 mL | 2.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2