Freselestat (ONO-6818)

Catalog No.: A12780
Neutrophil elastase inhibitor
Freselestat is a potent neutrophil elastase inhibitor. Freselestat reduces inflammatory mediators during simulated extracorporeal circulation. ONO-6818 significantly reduced interleukin 8 and C5b-9 production. ONO-6818 did not modulate changes of CD11b and L-selectin during recirculation.
Grouped product items
Product Name Price Stock Qty
Freselestat 5mg
$450.00
In stock
Freselestat 10mg
$850.00
In stock
Freselestat 25mg
$1,600.00
In stock
Freselestat 50mg
$3,000.00
In stock
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Biological Activity
Discription Freselestat is a potent neutrophil elastase inhibitor. Freselestat reduces inflammatory mediators during simulated extracorporeal circulation. ONO-6818 significantly reduced interleukin 8 and C5b-9 production. ONO-6818 did not modulate changes of CD11b and L-selectin during recirculation.
Product Information
Catalog Num A12780
Formula C23H28N6O4
Molecular Weight 452.51
CAS Number 208848-19-5
SMILES C3=C(C1=NC=C(C(N1CC(NC(C(C2=NN=C(O2)C(C)(C)C)=O)C(C)C)=O)=O)N)C=CC=C3
Synonyms ONO6818, ONO 6818
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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