Gemcitabine

Catalog No.: A11434
DNA synthesis inhibitor
Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Gemcitabine 100mg
$45.00
In stock
Gemcitabine 500mg
$135.00
In stock
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Adooq Products cited in reputable paper
Adooq's Gemcitabine has been cited by 3 publications
  • Yi-Ru Pan, .et al. , Int J Biol Sci, 2023, May 21;19(9):2772-2786 PMID: 37324940
  • Khan Mohammad Imran, .et al. , Pharmaceutics, 2023, May 24;15(6):1585 PMID: 37376034
  • Yi-Ru Pan, .et al. , Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
  • Biological Activity
    Discription Gemcitabine (LY 188011) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.
    Product Information
    Catalog Num A11434
    Formula C9H11F2N3O4
    Molecular Weight 263.2
    CAS Number 95058-81-4
    SMILES O=C1N(C=CC(N)=N1)[C@H]2C(F)([C@@H]([C@H](O2)CO)O)F
    Synonyms LY 188011, LY188011, LY-188011
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 47 mg/mL (178.56 mM)
    Water Warmed: 47 mg/mL (178.56 mM)
    Ethanol Insoluble
    In vivo water (warmed) 49 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 37.99 mL 189.97 mL 379.94 mL
    0.5 mM 7.6 mL 37.99 mL 75.99 mL
    1 mM 3.8 mL 19 mL 37.99 mL
    5 mM 0.76 mL 3.8 mL 7.6 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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