IITZ-01

Catalog No.: A20192
Lysosomotropic autophagy inhibitor
IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
Grouped product items
Product Name Price Stock Qty
IITZ-01 5mg
$80.00
In stock
IITZ-01 10mg
$140.00
In stock
IITZ-01 50mg
$420.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
Targets
Target Value
Product Information
Catalog Num A20192
Formula C26H23FN8O
Molecular Weight 482.51
CAS Number 1807988-47-1
SMILES FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1
Synonyms IITZ 01; IITZ01; Autophagy inhibitor IITZ-01
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (184.44 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.72 mL 103.62 mL 207.25 mL
0.5 mM 4.14 mL 20.72 mL 41.45 mL
1 mM 2.07 mL 10.36 mL 20.72 mL
5 mM 0.41 mL 2.07 mL 4.14 mL
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