JNJ-54175446

Catalog No.: A18675
P2X7 receptor antagonist
JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
Grouped product items
Product Name Price Stock Qty
JNJ-54175446 1mg
$480.00
In stock
JNJ-54175446 5mg
$880.00
In stock
JNJ-54175446 10mg
$1,380.00
In stock
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Biological Activity
Discription JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
Product Information
Catalog Num A18675
Formula C18H13ClF4N6O
Molecular Weight 440.78
CAS Number 1627902-21-9
SMILES ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F
Synonyms JNJ54175446, JNJ 54175446
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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