LXS196
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It can be used for the treatment of uveal melanoma. | ||
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Catalog Num | A19419 |
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Formula | C22H23F3N8O |
Molecular Weight | 472.47 |
CAS Number | 1874276-76-2 |
SMILES | NC1=C(C(NC2=C(N3CCC(C)(N)CC3)C=CC=N2)=O)N=C(C4=NC=CC=C4C(F)(F)F)C=N1 |
Synonyms | LXS 196, LXS-196 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 20 mg/mL (42.33 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (10.58 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.17 mL | 105.83 mL | 211.65 mL |
0.5 mM | 4.23 mL | 21.17 mL | 42.33 mL |
1 mM | 2.12 mL | 10.58 mL | 21.17 mL |
5 mM | 0.42 mL | 2.12 mL | 4.23 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2