Pradefovir mesylate

Catalog No.: A21644

liver CYP3A4 substrate

Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
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Product Name Price Stock Qty
Pradefovir mesylate 5mg
$495.00
In stock
Pradefovir mesylate 10mg
$853.00
In stock
Pradefovir mesylate 50mg
$2,530.00
In stock
Pradefovir mesylate 100mg
$5,060.00
In stock
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Biological Activity
Discription Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
Product Information
Catalog Num A21644
Formula C18H23ClN5O7PS
Molecular Weight 519.9
CAS Number 625095-61-6
SMILES NC1=C2N=CN(CCOC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C2=NC=N1.CS(=O)(O)=O
Synonyms Remofovir mesylate
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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