RET-IN-1

Catalog No.: A19015
RET inhibitor
RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
Grouped product items
Product Name Price Stock Qty
RET-IN-1 1mg
$320.00
In stock
RET-IN-1 5mg
$960.00
In stock
RET-IN-1 10mg
$1,600.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
Product Information
Catalog Num A19015
Formula C29H31N9O3
Molecular Weight 553.61
CAS Number 2222755-14-6
SMILES N#CC1=C2C(C3=NC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OC[C@H]7CNCCO7)=CN2N=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C1V1 = C2V2

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