RO-5963

Catalog No.: A18813
MDM2/MDMX inhibitor
RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53 with IC50s of ~17 nM and ~24 nM, respectively.
Grouped product items
Product Name Price Stock Qty
RO-5963 5mg
$350.00
In stock
RO-5963 10mg
$650.00
In stock
RO-5963 50mg
$2,000.00
In stock
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Biological Activity
Discription RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53 with IC50s of ~17 nM and ~24 nM, respectively.
Product Information
Catalog Num A18813
Formula C24H21ClF2N4O5
Molecular Weight 518.9
CAS Number 1416663-77-8
SMILES O=C(NC(CO)CO)C(N(C(N/C1=C\C2=CNC3=C2C=CC(Cl)=C3C)=O)C1=O)C4=CC=C(F)C(F)=C4
Synonyms RO-5963; RO 5963; RO5963;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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