RSL3

Catalog No.: A15865
Ferroptosis inhibitor
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
Grouped product items
Product Name Price Stock Qty
RSL3 5mg
$81.00
In stock
RSL3 10mg
$138.00
In stock
RSL3 25mg
$243.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's RSL3 has been cited by 4 publications
  • Qingyu Zhang, .et al. , Cell Death Discov, 2023, Mar 8;9(1):83 PMID: 36882396
  • Sampilvanjil A, .et al. , Am J Physiol Heart Circ Physiol, 2020, Mar 1;318(3):H508-H518 PMID: 31975626
  • Fujiki K, .et al. , Cell Death Differ, 2019, Feb 25 PMID: 30804470
  • Samantha W. Alvarez, .et al. , Nature, 2017, Nov 30; 551(7682): 639-643 PMID: 29168506
  • Biological Activity
    Discription RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.
    Targets
    Target Value
    Product Information
    Catalog Num A15865
    Formula C23H21ClN2O5
    Molecular Weight 440.88
    CAS Number 1219810-16-8
    SMILES COC(C1=CC=C([C@@]2([H])C3=C(C4=CC=CC=C4N3)C[C@](N2C(CCl)=O)([H])C(OC)=O)C=C1)=O
    Synonyms 1S,3R-RSL3
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 82 mg/mL (185.99 mM)
    Water Insoluble
    Ethanol 20 mg/mL
    In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.68 mL 113.41 mL 226.82 mL
    0.5 mM 4.54 mL 22.68 mL 45.36 mL
    1 mM 2.27 mL 11.34 mL 22.68 mL
    5 mM 0.45 mL 2.27 mL 4.54 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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