Streptozotocin (Zanosar)

Catalog No.: A10868
O-GlcNAcase inhibitor
Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.
Grouped product items
Product Name Price Stock Qty
Streptozotocin 500mg
$100.00
In stock
Streptozotocin 1g
$170.00
In stock
Streptozotocin (Zanosar) 10mM * 1mL in DMSO
$60.00
In stock
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Important Notice: For research use only. We do not sell to patients.

Prop65 Warning  WARNING: Attention California Residents: This product can expose you to chemicals including Streptozotocin (Zanosar) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Adooq Products cited in reputable paper
Adooq's Streptozotocin (Zanosar) has been cited by 10 publications
  • Zhen Liang, .et al. , Nat Metab, 2023, Jan;5(1):29-40 PMID: 36624157
  • Alemayehu Toma, .et al. , J Exp Pharmacol, 2022, 14: 309-316 PMID: 36317069
  • Andressa Braga, .et al. , Braz J Pharm Sci, 2022, 58: e19674
  • Yuanyuan Du, .et al. , Nat Med, 2022, Feb;28(2):272-282 PMID: 35115708
  • Karemah A. Alatawi, .et al. , Saudi Journal of Biological Sciences, 2021, 25 June
  • D.H. Mhya, .et al. , Asian J Exp Biol Sci, 2019, 12 (2): 164-172
  • Stanley I. R. Okoduwa, .et al. , J Diabetol, 2017, 8(3): 74-85
  • Stanley I. R. Okoduwa, .et al. , Medicines (Basel), 2017, Dec; 4(4): 73 PMID: 29019956
  • Stanley I. R. Okoduwa, .et al. , PLoS One, 2017, 12(1): e0170971 PMID: 28129400
  • Stanley I. R. Okoduwa, .et al. , World J Diabetes, 2016, Dec 15; 7(20): 605-614 PMID: 28031778
  • Biological Activity
    Discription Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.
    Product Information
    Catalog Num A10868
    Formula C8H15N3O7
    Molecular Weight 265.2
    CAS Number 18883-66-4
    SMILES CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
    Synonyms Streptozocin, Zanosar, STZ
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 51 mg/mL (192.29 mM)
    Water 51 mg/mL (192.29 mM)
    Ethanol Insoluble
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 37.71 mL 188.54 mL 377.07 mL
    0.5 mM 7.54 mL 37.71 mL 75.41 mL
    1 mM 3.77 mL 18.85 mL 37.71 mL
    5 mM 0.75 mL 3.77 mL 7.54 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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