Sulfatinib

Catalog No.: A21915
tyrosine kinase inhibitor
Sulfatinib (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC50s of in a range of 1 to 24 nM.
Grouped product items
Product Name Price Stock Qty
Sulfatinib 1mg
$45.00
In stock
Sulfatinib 5mg
$135.00
In stock
Sulfatinib 10mg
$230.00
In stock
Sulfatinib 50mg
$690.00
In stock
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Biological Activity
Discription Sulfatinib (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC50s of in a range of 1 to 24 nM.
Targets
Target Value
Product Information
Catalog Num A21915
Formula C24H28N6O3S
Molecular Weight 480.58
CAS Number 1308672-74-3
SMILES O=S(CC1=CC=CC(NC2=NC=CC(OC3=CC4=C(NC(C)=C4)C=C3)=N2)=C1)(NCCN(C)C)=O
Synonyms HMPL-012, HMPL012, HMPL 012
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (191.43 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.04 mL 208.08 mL
0.5 mM 4.16 mL 20.81 mL 41.62 mL
1 mM 2.08 mL 10.4 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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