SAG hydrochloride

Catalog No.: A21678
Smo receptor agonist
SAG (hydrochloride) is a potent Smo receptor agonist, and activates the Hedgehog signaling pathway, with a Kd of 59 nM.
Grouped product items
Product Name Price Stock Qty
SAG hydrochloride 1mg
$54.00
In stock
SAG hydrochloride 5mg
$162.00
In stock
SAG hydrochloride 10mg
$276.00
In stock
SAG hydrochloride 50mg
$828.00
In stock
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Biological Activity
Discription SAG (hydrochloride) is a potent Smo receptor agonist, and activates the Hedgehog signaling pathway, with a Kd of 59 nM.
Product Information
Catalog Num A21678
Formula C28H29Cl2N3OS
Molecular Weight 526.52
CAS Number 2095432-58-7
SMILES O=C(C1=C(Cl)C2=CC=CC=C2S1)N([C@H]3CC[C@H](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 69 mg/mL (131.04 mM)
Water 97 mg/mL (184.22 mM)
Ethanol Warmed: 39 mg/mL (74.07 mM)
In vivo water 95 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.99 mL 94.96 mL 189.93 mL
0.5 mM 3.8 mL 18.99 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 18.99 mL
5 mM 0.38 mL 1.9 mL 3.8 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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