TM5441

Catalog No.: A19369
PAI-1 inhibitor
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.
Grouped product items
Product Name Price Stock Qty
TM5441 2mg
$80.00
In stock
TM5441 5mg
$130.00
In stock
TM5441 10mg
$200.00
In stock
TM5441 50mg
$720.00
In stock
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Biological Activity
Discription TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.
Product Information
Catalog Num A19369
Formula C21H17ClN2O6
Molecular Weight 428.82
CAS Number 1190221-43-2
SMILES ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1
Synonyms M-5441; TM 5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 83 mg/mL (193.55 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.32 mL 116.6 mL 233.2 mL
0.5 mM 4.66 mL 23.32 mL 46.64 mL
1 mM 2.33 mL 11.66 mL 23.32 mL
5 mM 0.47 mL 2.33 mL 4.66 mL
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