TPCA-1

Catalog No.: A11579
IKK-2 inhibitor
TPCA-1 is a potent and selective inhibitor of human IκB kinase-2 (IKK-2) with IC50 = 17.9 nM for IKK-2 compared to 400nm for IKK-1.
Grouped product items
Product Name Price Stock Qty
TPCA-1 10mg
$120.00
In stock
TPCA-1 25mg
$250.00
In stock
TPCA-1 50mg
$420.00
In stock
TPCA-1 100mg
$535.00
In stock
TPCA-1 10mM * 1mL in DMSO
$80.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription TPCA-1 is a potent and selective inhibitor of human IκB kinase-2 (IKK-2) with IC50 = 17.9 nM for IKK-2 compared to 400nm for IKK-1.
Targets
Target Value
Product Information
Catalog Num A11579
Formula C12H10FN3O2S
Molecular Weight 279.29
CAS Number 507475-17-4
SMILES C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
Synonyms TPCA1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 49 mg/mL (175.44 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.03 mL 358.05 mL
0.5 mM 7.16 mL 35.81 mL 71.61 mL
1 mM 3.58 mL 17.9 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy TPCA-1 | TPCA-1 Supplier | purchase TPCA-1 | TPCA-1 cost | TPCA-1 manufacturer | order TPCA-1 | TPCA-1 distributor | buy 507475-17-4 | 507475-17-4 Supplier | purchase 507475-17-4 | 507475-17-4 cost | 507475-17-4 manufacturer | order 507475-17-4 | 507475-17-4 distributor