Wedelolactone

Catalog No.: A14804
IKK Inhibitor II
Wedelolactone, a compound originally extracted from Eclipta alba, has been shown to inhibit caspase-11, which is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis.
Grouped product items
Product Name Price Stock Qty
Wedelolactone 10mg
$140.00
In stock
Wedelolactone 25mg
$280.00
In stock
Wedelolactone 50mg
$500.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Wedelolactone has been cited by 1 publications
  • Shigetoshi Yokoyama, .et al. , eLife, 2018, 7: e37854 PMID: 30526845
  • Biological Activity
    Discription Wedelolactone, a compound originally extracted from Eclipta alba, has been shown to inhibit caspase-11, which is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis.
    Targets
    Target Value
    Product Information
    Catalog Num A14804
    Formula C16H10O7
    Molecular Weight 314.3
    CAS Number 524-12-9
    SMILES COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O
    Synonyms IKK Inhibitor II, Eclipta alba
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 60 mg/mL (190.92 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.82 mL 159.08 mL 318.17 mL
    0.5 mM 6.36 mL 31.82 mL 63.63 mL
    1 mM 3.18 mL 15.91 mL 31.82 mL
    5 mM 0.64 mL 3.18 mL 6.36 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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