WS-383

Catalog No.: A21483
DCN1-UBC12 interaction inhibitor
WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2.
Grouped product items
Product Name Price Stock Qty
WS-383 1mg
$320.00
In stock
WS-383 5mg
$960.00
In stock
WS-383 10mg
$1,600.00
In stock
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Biological Activity
Discription WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2.
Product Information
Catalog Num A21483
Formula C18H21Cl2N9S2
Molecular Weight 498.46
CAS Number 2247544-02-9
SMILES CN(C)CCN1N=NN=C1SC2=CC(C)=NC3=NC(SCC4=CC=C(Cl)C=C4)=NN23.Cl
Synonyms WS383, WS 383
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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