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ZXH-3-26

Catalog No.: A18399
PROTAC BRD4 degrader
ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.
ZXH-3-26
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ZXH-3-26 5mg
ZXH-3-26 10mg
ZXH-3-26 50mg
ZXH-3-26 100mg
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Biological Activity
Discription ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.
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Target Value
Product Information
Catalog Num A18399
Formula C38H37ClN8O7S
Molecular Weight 785.27
CAS Number 2243076-67-5
SMILES O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1
Synonyms ZXH326, ZXH-326
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Epigenetics > Epigenetic Reader Domain
PROTACs > PROTAC Degrader
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