2,4-Pyridinedicarboxylic Acid

Catalog No.: A16372
KDM inhibitor
2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is an inhibitor of histone lysine-specific demethylases that targets on JMJD2A (KDM4A), KDM4C, KDM4E (IC50, 1.4 μM), KDM5B (IC50, 3 μM), KDM6A and other 2-oxogynases.
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Product Name Price Stock Qty
2,4-Pyridinedicarboxylic Acid 50000mg
$80.00
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Biological Activity
Discription 2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is an inhibitor of histone lysine-specific demethylases that targets on JMJD2A (KDM4A), KDM4C, KDM4E (IC50, 1.4 μM), KDM5B (IC50, 3 μM), KDM6A and other 2-oxogynases.
Product Information
Catalog Num A16372
Formula C7H5NO4
Molecular Weight 167.12
CAS Number 499-80-9
SMILES O=C(O)C1=CC(C(O)=O)=NC=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 30 mg/mL (179.51 mM)
Water Insoluble
Ethanol 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 59.84 mL 299.19 mL 598.37 mL
0.5 mM 11.97 mL 59.84 mL 119.67 mL
1 mM 5.98 mL 29.92 mL 59.84 mL
5 mM 1.2 mL 5.98 mL 11.97 mL
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