MK-6096 (Filorexant)

Catalog No.: A13168
Orexin receptor antagonist
MK6096, also known as filorexant, is an orally bioavailable potent and selective reversible antagonist of OX(1)R and OX(2)R currently in clinical development for insomnia. MK-6096 demonstrated potent binding and antagonism of both human OX(1)R and OX(2)R (<3 nM in binding, 11 nM in FLIPR), with no significant off-target activities against a panel of >170 receptors and enzymes.
Grouped product items
Product Name Price Stock Qty
MK-6096 (Filorexant) 5mg
$75.00
In stock
MK-6096 (Filorexant) 25mg
$270.00
In stock
MK-6096 (Filorexant) 100mg
$650.00
In stock
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Biological Activity
Discription MK6096, also known as filorexant, is an orally bioavailable potent and selective reversible antagonist of OX(1)R and OX(2)R currently in clinical development for insomnia. MK-6096 demonstrated potent binding and antagonism of both human OX(1)R and OX(2)R (<3 nM in binding, 11 nM in FLIPR), with no significant off-target activities against a panel of >170 receptors and enzymes.
Product Information
Catalog Num A13168
Formula C24H25FN4O2
Molecular Weight 420.48
CAS Number 1088991-73-4
SMILES CC1=CC=C(C2=NC=CC=N2)C(C(N3C[C@@H](COC4=NC=C(F)C=C4)CC[C@@H]3C)=O)=C1
Synonyms MK6096, MK-6096, MK 6096
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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