ML224

Catalog No.: A21633
TSHR inverse agonist
ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimulated cAMP production with an IC50 = 2.3 μM.
Grouped product items
Product Name Price Stock Qty
ML224 5mg
$135.00
In stock
ML224 10mg
$233.00
In stock
ML224 50mg
$690.00
In stock
ML224 100mg
$1,380.00
In stock
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Biological Activity
Discription ML224(NCGC00242364; ANTAG3) is a selective TSHR inverse agonist; inhibits TSH-stimulated cAMP production with an IC50 = 2.3 μM.
Targets
Target Value
Product Information
Catalog Num A21633
Formula C31H31N3O5
Molecular Weight 525.59
CAS Number 1338824-21-7
SMILES CC(NC1=CC(C)=C(OCC2=CC(C(N3CC4=CC=CO4)NC5=C(C=CC=C5)C3=O)=CC=C2OC)C(C)=C1)=O
Synonyms NCGC00242364, NCGC 00242364, NCGC-00242364; ANTAG3, ANTAG-3; ML 224, ML-224
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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