ML221
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays. |
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Catalog Num | A19446 |
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Formula | C17H11N3O6S |
Molecular Weight | 385.35 |
CAS Number | 877636-42-5 |
SMILES | O=C1C=C(CSC2=NC=CC=N2)OC=C1OC(C3=CC=C([N+]([O-])=O)C=C3)=O |
Synonyms | ML 221, ML-221 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 8 mg/mL (20.76 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.95 mL | 129.75 mL | 259.5 mL |
0.5 mM | 5.19 mL | 25.95 mL | 51.9 mL |
1 mM | 2.6 mL | 12.98 mL | 25.95 mL |
5 mM | 0.52 mL | 2.6 mL | 5.19 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2