MLN4924 (Pevonedistat)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. |
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Catalog Num | A11260 |
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Formula | C21H25N5O4S |
Molecular Weight | 443.5 |
CAS Number | 905579-51-3 |
SMILES | C1CC2=CC=CC=C2[C@H]1NC3=NC=NC4=C3C=CN4[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N |
Synonyms | MLN-4924 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 78 mg/mL (175.86 mM) | |
Water | Insoluble | ||
Ethanol | 78 mg/mL | ||
In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 19 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.55 mL | 112.74 mL | 225.48 mL |
0.5 mM | 4.51 mL | 22.55 mL | 45.1 mL |
1 mM | 2.25 mL | 11.27 mL | 22.55 mL |
5 mM | 0.45 mL | 2.25 mL | 4.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2