MMV008138

Catalog No.: A19169
targeting antimalarial agent
MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
Grouped product items
Product Name Price Stock Qty
MMV008138 5mg
$360.00
In stock
MMV008138 10mg
$620.00
In stock
MMV008138 50mg
$1,840.00
In stock
MMV008138 100mg
$3,680.00
In stock
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Biological Activity
Discription MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
Product Information
Catalog Num A19169
Formula C18H14Cl2N2O2
Molecular Weight 361.22
CAS Number 1679333-73-3
SMILES O=C([C@@H]1CC2=C([C@@H](C3=CC=C(Cl)C=C3Cl)N1)NC4=C2C=CC=C4)O
Synonyms MMV 008138, MMV-008138
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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