N-Acetylglucosamine

Catalog No.: A17841
Elastase release inhibitor
Acetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8?C17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92?C100%).
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N-Acetylglucosamine 500mg
$50.00
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Biological Activity
Discription Acetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8?C17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92?C100%).
Targets
Target Value
Product Information
Catalog Num A17841
Formula C8H15NO6
Molecular Weight 221.21
CAS Number 7512-17-6
SMILES O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)NC(C)=O
Synonyms Acetylglucosamine; GlcNAc; Bio-NAG; GreenNAG; Marine Sweet; N-Acetyl-D-glucosamine; N-Acetylglucosamine; NSC 400525; NSC 524344.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 43 mg/mL (194.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 45.21 mL 226.03 mL 452.06 mL
0.5 mM 9.04 mL 45.21 mL 90.41 mL
1 mM 4.52 mL 22.6 mL 45.21 mL
5 mM 0.9 mL 4.52 mL 9.04 mL
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