NCT-503

Catalog No.: A17132
PHGDH inhibitor
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 value of 2.5 μM.
Grouped product items
Product Name Price Stock Qty
NCT-503 5mg
$50.00
In stock
NCT-503 10mg
$90.00
In stock
NCT-503 50mg
$360.00
In stock
NCT-503 100mg
$680.00
In stock
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Biological Activity
Discription NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 value of 2.5 μM.
Product Information
Catalog Num A17132
Formula C20H23F3N4S
Molecular Weight 408.5
CAS Number 1916571-90-8
SMILES S=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2)CC1)NC3=NC(C)=CC(C)=C3
Synonyms NCT503, NCT 503
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 73 mg/mL (178.71 mM)
Water Insoluble
Ethanol 73 mg/mL (178.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.48 mL 122.4 mL 244.8 mL
0.5 mM 4.9 mL 24.48 mL 48.96 mL
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.9 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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