Avadomide (CC-122)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Avadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN. |
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Catalog Num | A16854 |
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Formula | C14H14N4O3 |
Molecular Weight | 286.29 |
CAS Number | 1015474-32-4 |
SMILES | O=C(C(N1C(C)=NC2=C(C(N)=CC=C2)C1=O)CC3)NC3=O |
Synonyms | CC122, CC 122 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 50 mg/mL (174.64 mM) | |
Water | Insoluble | ||
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 34.93 mL | 174.65 mL | 349.3 mL |
0.5 mM | 6.99 mL | 34.93 mL | 69.86 mL |
1 mM | 3.49 mL | 17.46 mL | 34.93 mL |
5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2