Aprocitentan

Catalog No.: A21999
dual ETA/ETB antagonist
Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
Grouped product items
Product Name Price Stock Qty
Aprocitentan 5mg
$280.00
In stock
Aprocitentan 10mg
$400.00
In stock
Aprocitentan 50mg
$1,200.00
In stock
Aprocitentan 100mg
$1,800.00
In stock
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Biological Activity
Discription Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
Targets
Target Value
Product Information
Catalog Num A21999
Formula C16H14Br2N6O4S
Molecular Weight 546.19
CAS Number 1103522-45-7
SMILES O=S(N)(NC1=NC=NC(OCCOC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O
Synonyms ACT-132577,ACT132577, ACT 132577
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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This equation is commonly abbreviated as: C1V1 = C2V2

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