AR-A 014418

Catalog No.: A13728
GSK-3 inhibitor
AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.
Grouped product items
Product Name Price Stock Qty
AR-A 014418 10mg
$60.00
In stock
AR-A 014418 25mg
$120.00
In stock
AR-A 014418 50mg
$200.00
In stock
AR-A 014418 100mg
$350.00
In stock
AR-A 014418 10mM * 1mL in DMSO
$60.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's AR-A 014418 has been cited by 1 publications
  • Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283
  • Biological Activity
    Discription AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.
    Targets
    Target Value
    Product Information
    Catalog Num A13728
    Formula C12H12N4O4S
    Molecular Weight 308.31
    CAS Number 487021-52-3
    SMILES COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
    Synonyms AR-A014418, ARA 014418, ARA014418
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 55 mg/mL (178.39 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 32.43 mL 162.17 mL 324.35 mL
    0.5 mM 6.49 mL 32.43 mL 64.87 mL
    1 mM 3.24 mL 16.22 mL 32.43 mL
    5 mM 0.65 mL 3.24 mL 6.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy AR-A 014418 | AR-A 014418 Supplier | purchase AR-A 014418 | AR-A 014418 cost | AR-A 014418 manufacturer | order AR-A 014418 | AR-A 014418 distributor | buy 487021-52-3 | 487021-52-3 Supplier | purchase 487021-52-3 | 487021-52-3 cost | 487021-52-3 manufacturer | order 487021-52-3 | 487021-52-3 distributor