AR-A 014418
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices. | ||
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Catalog Num | A13728 |
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Formula | C12H12N4O4S |
Molecular Weight | 308.31 |
CAS Number | 487021-52-3 |
SMILES | COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-] |
Synonyms | AR-A014418, ARA 014418, ARA014418 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 55 mg/mL (178.39 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.43 mL | 162.17 mL | 324.35 mL |
0.5 mM | 6.49 mL | 32.43 mL | 64.87 mL |
1 mM | 3.24 mL | 16.22 mL | 32.43 mL |
5 mM | 0.65 mL | 3.24 mL | 6.49 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2