BI-1347

Catalog No.: A18769
CDK8 inhibitor
BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM.
Grouped product items
Product Name Price Stock Qty
BI-1347 5mg
$90.00
In stock
BI-1347 10mg
$140.00
In stock
BI-1347 50mg
$520.00
In stock
BI-1347 100mg
$880.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM.
Targets
Target Value
Product Information
Catalog Num A18769
Formula C22H20N4O
Molecular Weight 356.43
CAS Number 2163056-91-3
SMILES O=C(N(C)C)CN1N=CC(C2=CC=C(C3=CN=CC4=C3C=CC=C4)C=C2)=C1
Synonyms BI-1347; BI1347; BI 1347
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 70 mg/mL (196.39 mM)
Water Insoluble
Ethanol 3 mg/mL (8.41 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.28 mL 280.56 mL
0.5 mM 5.61 mL 28.06 mL 56.11 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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