CADD522

Catalog No.: A19399
RUNX2-DNA binding inhibitor
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity.
Grouped product items
Product Name Price Stock Qty
CADD522 5mg
$50.00
In stock
CADD522 10mg
$70.00
In stock
CADD522 50mg
$250.00
In stock
CADD522 100mg
$420.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's CADD522 has been cited by 1 publications
  • Jiten R Sharma, .et al. , Life Sci, 2023, Apr 1;318:121480 PMID: 36775116
  • Biological Activity
    Discription CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity.
    Product Information
    Catalog Num A19399
    Formula C15H13Cl2NO3
    Molecular Weight 326.17
    CAS Number 199735-88-1
    SMILES ClC1=C(Cl)C=CC(NC(C2C(C3)C=CC3C2C(O)=O)=O)=C1
    Synonyms CADD 522, CADD-522
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 58 mg/mL (177.82 mM)
    Water Insoluble
    Ethanol 58 mg/mL (177.82 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.66 mL 153.29 mL 306.59 mL
    0.5 mM 6.13 mL 30.66 mL 61.32 mL
    1 mM 3.07 mL 15.33 mL 30.66 mL
    5 mM 0.61 mL 3.07 mL 6.13 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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