Signaling Pathway
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| Discription | CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM). | ||
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| Targets |
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| Catalog Num | A21467 |
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| Formula | C15H15FN6O2S2 |
| Molecular Weight | 394.45 |
| CAS Number | 1421693-22-2 |
| SMILES | CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1 |
| Synonyms | CDKI73, CDKI 73, LS-007 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 77 mg/mL (195.2 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (2.53 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.35 mL | 126.76 mL | 253.52 mL |
| 0.5 mM | 5.07 mL | 25.35 mL | 50.7 mL |
| 1 mM | 2.54 mL | 12.68 mL | 25.35 mL |
| 5 mM | 0.51 mL | 2.54 mL | 5.07 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
