CHMFL-EGFR-202

Catalog No.: A12524
EGFR inhibitor
CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively.
Grouped product items
Product Name Price Stock Qty
CHMFL-EGFR-202 1mg
$320.00
In stock
CHMFL-EGFR-202 5mg
$960.00
In stock
CHMFL-EGFR-202 10mg
$1,600.00
In stock
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Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription CHMFL-EGFR-202 is a potent, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant kinase, with IC50s of 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases, respectively.
Targets
Target Value
Product Information
Catalog Num A12524
Formula C25H24ClN7O2
Molecular Weight 489.96
CAS Number 2089381-40-6
SMILES O=C(N(C1)CCC[C@H]1N2C3=NC=NC(N)=C3C(C4=CC(Cl)=C(OCC5=NC=CC=C5)C=C4)=N2)C=C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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