Zegocractin (CM-4620)

Catalog No.: A19452
CRAC inhibitor
CM-4620 is a calcium-release activated calcium-channel (CRAC) inhibitor, with IC50s of 119, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively.
Grouped product items
Product Name Price Stock Qty
CM-4620 5mg
$300.00
In stock
CM-4620 10mg
$500.00
In stock
CM-4620 50mg
$1,770.00
In stock
CM-4620 100mg
$2,800.00
In stock
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Biological Activity
Discription CM-4620 is a calcium-release activated calcium-channel (CRAC) inhibitor, with IC50s of 119, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively.
Product Information
Catalog Num A19452
Formula C19H11ClF3N3O3
Molecular Weight 421.76
CAS Number 1713240-67-5
SMILES O=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F
Synonyms CM4620, CM 4620
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (218.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.71 mL 118.55 mL 237.1 mL
0.5 mM 4.74 mL 23.71 mL 47.42 mL
1 mM 2.37 mL 11.86 mL 23.71 mL
5 mM 0.47 mL 2.37 mL 4.74 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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