CMP3a

Catalog No.: A18347
NEK2 kinase inhibitor
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Grouped product items
Product Name Price Stock Qty
CMP3a 5mg
$350.00
In stock
CMP3a 10mg
$550.00
In stock
CMP3a 50mg
$1,850.00
In stock
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Biological Activity
Discription CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Product Information
Catalog Num A18347
Formula C28H27F3N6O2S
Molecular Weight 568.6192
CAS Number 2225902-88-3
SMILES O=C(C1=C(O[C@@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N
Synonyms CMP 3a, CMP-3a
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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