COH000

Catalog No.: A17122
SUMO E1 Inhibitor
COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.
Grouped product items
Product Name Price Stock Qty
COH000 5mg
$450.00
In stock
COH000 10mg
$750.00
In stock
COH000 50mg
$2,000.00
In stock
COH000 100mg
$3,200.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.
Product Information
Catalog Num A17122
Formula C25H25NO5
Molecular Weight 419.48
CAS Number 1534358-79-6
SMILES O=C(C1=C(C(OC)=O)C2C=CC1([C@H](NC3=CC=CC=C3)CC4=CC=C(C)C=C4)O2)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 47 mg/mL (112.04 mM)
Water Insoluble
Ethanol 1 mg/mL (2.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.2 mL 238.39 mL
0.5 mM 4.77 mL 23.84 mL 47.68 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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