Fimasartan

Catalog No.: A17477
non-peptide angiotensin II receptor antagonist
Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys.
Grouped product items
Product Name Price Stock Qty
Fimasartan 5mg
$50.00
In stock
Fimasartan 10mg
$80.00
In stock
Fimasartan 50mg
$150.00
In stock
Fimasartan 100mg
$240.00
In stock
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Biological Activity
Discription Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys.
Targets
Target Value
Product Information
Catalog Num A17477
Formula C27H31N7OS
Molecular Weight 501.65
CAS Number 247257-48-3
SMILES S=C(N(C)C)CC1=C(C)N=C(CCCC)N(CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C1=O
Synonyms BR-A657; BR A657; BRA657; BRA 657; Fimasartan. brand name: Kanarb.
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 97 mg/mL (193.36 mM)
Ethanol 23 mg/mL (45.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.93 mL 99.67 mL 199.34 mL
0.5 mM 3.99 mL 19.93 mL 39.87 mL
1 mM 1.99 mL 9.97 mL 19.93 mL
5 mM 0.4 mL 1.99 mL 3.99 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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