GDC-0575 (ARRY-575, RG7741)
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2?nM. |
---|
Catalog Num | A16811 |
---|---|
Formula | C16H20BrN5O |
Molecular Weight | 378.27 |
CAS Number | 1196541-47-5 |
SMILES | O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32 |
Synonyms | GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476; |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 68 mg/mL (179.76 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (13.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.44 mL | 132.18 mL | 264.36 mL |
0.5 mM | 5.29 mL | 26.44 mL | 52.87 mL |
1 mM | 2.64 mL | 13.22 mL | 26.44 mL |
5 mM | 0.53 mL | 2.64 mL | 5.29 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2