Go 6976
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3. | ||
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Targets |
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Catalog Num | A12419 |
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Formula | C24H18N4O |
Molecular Weight | 378.43 |
CAS Number | 136194-77-9 |
SMILES | CN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O |
Synonyms | Go6976, Go-6976 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 18 mg/mL (47.69 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 0.5% CMC Na+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.42 mL | 132.12 mL | 264.25 mL |
0.5 mM | 5.28 mL | 26.42 mL | 52.85 mL |
1 mM | 2.64 mL | 13.21 mL | 26.42 mL |
5 mM | 0.53 mL | 2.64 mL | 5.28 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2