GSK1324726A (I-BET726)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | GSK1324726A (I-BET726) is a novel, potent, and selective small molecule inhibitor of BET proteins with high affinity to BRD2 (IC50= 41 nM), BRD3 (IC50= 31 nM), and BRD4 (IC50= 22 nM). | ||
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Catalog Num | A14133 |
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Formula | C25H23ClN2O3 |
Molecular Weight | 434.91 |
CAS Number | 1300031-52-0 |
SMILES | CC1CC(C2=C(N1C(=O)C)C=CC(=C2)C3=CC=C(C=C3)C(=O)O)NC4=CC=C(C=C4)Cl |
Synonyms | I-BET726, GSK 1324726A, GSK-1324726A, I-BET 726 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 77 mg/mL (177.05 mM) | |
Water | Insoluble | ||
Ethanol | 77 mg/mL (177.05 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.99 mL | 114.97 mL | 229.93 mL |
0.5 mM | 4.6 mL | 22.99 mL | 45.99 mL |
1 mM | 2.3 mL | 11.5 mL | 22.99 mL |
5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2