JNJ-38877618
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | JNJ-38877618 is a novel potent, highly selective, orally bioavailable c-Met tyrosine kinase inhibitor with Kd of 1.2, 2.1 and 21 nM for WT, M1250T and Y1235D mutants MET, respectively. |
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Catalog Num | A18325 |
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Formula | C20H12F2N6 |
Molecular Weight | 374.355 |
CAS Number | 943540-74-7 |
SMILES | FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43 |
Synonyms | JNJ38877618, JNJ 38877618 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 9 mg/mL (24.04 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.71 mL | 133.56 mL | 267.13 mL |
0.5 mM | 5.34 mL | 26.71 mL | 53.43 mL |
1 mM | 2.67 mL | 13.36 mL | 26.71 mL |
5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2